The Genetics of Parkinson's Disease

http://www.medscape.com/viewarticle/528722_3

Dominantly Inherited Parkinson Disease: Probable Gain-of-Function Mechanism

• SNCA / Park 1 / Park 4
• LRRK2 / Park 8

Recessively Inherited Parkinson Disease: Probable Loss-of-Function Mechanism

• Parkin / Park 2 -> early-onset
• PINK1
• DJ1

http://adam.about.net/reports/Parkinson-s-disease.htm