Friday, November 25, 2011

ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression

ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression

Summary: We introduce ProfileChaser, a web server that allows for querying the Gene Expression Omnibus based on genome-wide patterns of differential expression. Using a novel, content-based approach, ProfileChaser retrieves expression profiles that match the differentially regulated transcriptional programs in a user-supplied experiment. This analysis identifies statistical links to similar expression experiments from the vast array of publicly available data on diseases, drugs, phenotypes and other experimental conditions.

Availability: http://profilechaser.stanford.edu

Contact: abutte@stanford.edu

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