Gene expression: The dynamics of the brain transcriptome revealed

Gene expression: The dynamics of the brain transcriptome revealed

The tight regulation of gene expression in space and time is key to understanding how the complexity and variation within and between organisms can arise from a relatively simple DNA blueprint. Until now, few studies had been able to characterize the temporal dynamics of gene transcription in the human brain with the depth reported in two recent papers published in Nature.

http://www.nature.com.proxy.lib.sfu.ca/nrn/journal/v12/n12/full/nrn3145.html?WT.ec_id=NRN-201112

1. Kang, H. J. et al. Spatio–temporal transcriptome of the human brain. Nature 478, 483–489 (2011)
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2. Colantuoni, C. et al. Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature 478, 519–524 (2011).
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