Jay Bradner: Open-source cancer research

http://www.ted.com/talks/jay_bradner_open_source_cancer_research.html

And so please consider this a work in progress, but I'd like to tell you today a story about a very rare cancer called midline carcinoma, about the protein target, the undruggable protein target that causes this cancer, called BRD4, and about a molecule developed at my lab at Dana Farber Cancer Institute called JQ1, which we affectionately named for Jun Qi, the chemist that made this molecule. Now BRD4 is an interesting protein.