"This discovery provides direct evidence that Parkinson's may result from gene-environmental interactions," Farrer says. "The resulting impairment highlights neuronal recycling systems as a focal point in the effort to develop more effective drugs."
The mutation, EIF4G1, was found in a family from northern France that has a high rate of the disease – more than half of the members of each generation develop it.
http://www.eurekalert.org/pub_releases/2011-09/uobc-nig090711.php
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