Thursday, September 1, 2011

GENSAT - Gene Expression Nervous System ATlas, Sense Lab

http://www.ncbi.nlm.nih.gov/gensat

GENSAT stands for Gene Expression Nervous System ATlas. The GENSAT project aims to map the expression of all genes expressed in the mouse brain at various stages of development. The project focuses on two techniques
Evaluation of unmodified mice lines for expression of a given gene using radiolabelled riboprobes and in-situ hybridization.
Creation of transgenic mice lines containing a BAC construct that expresses a marker gene in the same environment as the native gene

The GENSAT project aims to map the expression of genes in the central nervous system of the mouse, using both in situ hybridization and transgenic mouse techniques.

http://neuronbank.org
The NeuronBank Wiki is place for Neuroscientists to describe neurons and neural circuitry. It works like Wikipedia, in that all pages are available to be edited by registered users of NeuronBank. The ultimate goal is advance the field of Neuromics by creating an encyclopedia of neurons and neural circuitry.

http://senselab.med.yale.edu/NeuronDB/ndbCanExpl.aspx
Canonical neurons and their parts
The abbreviations for the canonical parts of a neuron are: D, dendrite; S, soma (cell body); AH, axon hillock-initial segment of the axon; A, axon; T, axon terminal.
The simplest case is a single dendrite, represented as an equivalent cylinder (e) consisting of a chain of three compartments, designated as (p) proximal, (m) middle, and (d) distal with respect to the cell body

Cells have various forms. eg. Nigral dopaminergic cell has Canonical form 3

ModelDB, models of a particular neuron, citations, etc.
http://senselab.med.yale.edu/ModelDB/FindByRegionList.asp

borad cell types: Neuron, glia, muscle, gland

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