Monday, August 22, 2011

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2891.html

miR-128b is highly expressed in the frontal cortex, and its host gene, regulator of calmodulin signaling (Rcs, also known as Arpp21) is essential for mediating dopamine transmission9, which is critical in the ILPFC for the formation of fear-extinction memories10.

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