Functional Genomics Laboratory: Gingeras Group

http://gingeraslab.cshl.edu/

Expression and Proliferation Program. We are located in the Genome Center on the Woodbury campus. Our laboratory employs empirical and computational approaches to study the organization of information found within genomes and the roles non-protein coding RNAs assume both as part of the informational content and regulation of the protein coding content. Central to these studies is the analysis of the transcriptional content expressed by cells (transcriptomes) and the epigenetic marks found on both genomes and chromatin that influence the expression levels and timing of transcriptomes. These studies require whole genome analyses using high density microarray and deep nucleotide sequencing. The generation of such very large sets has prompted us to develop and to utilize novel computational tools: to store, to analyze, to curate, to graphically display and to make these data sets available for the scientific community.