GTEx is throwing away 90% of their data

http://liorpachter.wordpress.com/2013/10/21/gtex/

Ubuntu System Halted Won't Power Off

When you shutdown from Ubuntu, the system freezes, system hangs and does not power off.

Try this:

$ gksu gedit /etc/default/grub

GRUB_CMDLINE_LINUX="acpi=force pci=noacpi apm=power_off"

$ sudo update-grub

Or try disabling ACPI in the computer's BIOS.

Change Login Screen Wallpaper with Ubuntu Tweak

Ubuntu Tweak > Tweaks > Login Settings

Click the "Unlock" button at the top, pick a picture and voila!

Free audiobooks

Free audiobooks

http://librivox.org/

http://www.gutenberg.org/wiki/Gutenberg:The_Audio_Books_Project

God In My Everything

God In My Everything

Ken Shigematsu shows that spiritual formation is more than just solitude and contemplative reflections. Spiritual formation happens in the everyday, in each and every moment of life. For those caught up in the busyness of work, family, and church, it often feels like time with God is just another thing on a crowded 'to-do' list. Ken explains how the time-tested spiritual practice of the 'rule of life' can help bring busy people into a closer relationship with God. He shows how a personal rule of life can fit almost any vocation or life situation. In God in My Everything, you will discover how to create and practice a life-giving, sustainable rhythm in the midst of your demanding life. If you long for a deeper spirituality but often feel that the busyness of life makes a close relationship with God challenging---and, at times, seemingly impossible---this book is for you


http://www.goodreads.com/book/show/17133254-god-in-my-everything

The Double Helix : A Personal Account of the Discovery of the Structure of DNA

The Double Helix : A Personal Account of the Discovery of the Structure of DNA is an autobiographical account of the discovery of the double helixstructure of DNA written by James D. Watson and published in 1968. It was and remains a controversial account.

http://en.wikipedia.org/wiki/The_Double_Helix

Rap video by 7 graders
http://www.genomeweb.com/node/1296296 

E.C. Manning Provincial Park

Lightning Lake, Flash Lake, Strike Lake, Thunder lake

http://canadianveggie.wordpress.com/2011/08/11/greater-vancouver-hike-lightning-lakes-chain/

Surrogate variable analysis

http://www.bioconductor.org/packages/2.12/bioc/vignettes/sva/inst/doc/sva.pdf

The sva package contains functions for removing batch e ects and other unwanted variation
in high-throughput experiments. Speci cally, the sva package contains functions for identifying and building surrogate variables for high-dimensional data sets. Surrogate variables
are covariates constructed directly from high-dimensional data (like gene expression/RNA
sequencing/methylation/brain imaging data) that can be used in subsequent analyses to
adjust for unknown, unmodeled, or latent sources of noise.

Genes In Life .org

http://www.genesinlife.org/

Genes in Life is a place to learn about all the ways genetics is a part of your life. On this site you will learn how genetics affects you and your family, why you should talk to your healthcare providers about genetics, how to get involved in genetics research, and much more!

The computer — your Virgil in the world of atoms

http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2013/press.html

Chemists used to create models of molecules using plastic balls and sticks. Today, the modelling is carried out in computers. In the 1970s, Martin Karplus, Michael Levitt and Arieh Warshel laid the foundation for the powerful programs that are used to understand and predict chemical processes. Computer models mirroring real life have become crucial for most advances made in chemistry today.

Canadian author Alice Munro wins Nobel Prize for literature

http://www.ctvnews.ca/entertainment/canadian-author-alice-munro-wins-nobel-prize-for-literature-1.1491581

She is the first Canadian-born and raised writer, and the 13th woman to win the award.

Munro's bestselling collection of stories include "Dance of the Happy Shades," "Who Do You Think You Are?," "Friend of My Youth," "Hateship, Friendship, Courtship, Loveship, Marriage," "Too Much Happiness, and most recently "Dear Life."

Read more: http://www.ctvnews.ca/entertainment/canadian-author-alice-munro-wins-nobel-prize-for-literature-1.1491581#ixzz2hKvUxr6t

Statistics on how many reads are found in the intron

Total RNA sequencing reveals nascent transcription and
widespread co-transcriptional splicing in the human brain
http://www.nature.com/nsmb/journal/v18/n12/pdf/nsmb.2143.pdf

- around 40% mapped to introns
- fetal brain > adult brain > liver

Ribo-Zero Gold Kit: improved RNA-seq results after
removal of cytoplasmic and mitochondrial ribosomal
RNA

http://www.nature.com/nmeth/journal/v8/n11/pdf/nmeth.f.352.pdf%3FWT.ec_id%3DNMETH-201111

- around 32% mapped to introns

The anatomy of successful computational biology software

http://www.nature.com/nbt/journal/v31/n10/full/nbt.2721.html?WT.ec_id=NBT-201310

The year was 1989 and Stephen Altschul had a problem. Sam Karlin, the brilliant mathematician whose help he needed, was so convinced of the power of a mathematically tractable but biologically constrained measure of protein sequence similarity that he would not listen to Altschul (or anyone else for that matter). So Altschul essentially tricked him into solving the problem stymying the field of computational biology by posing it in terms of pure mathematics, devoid of any reference to biology. The treat from that trick became known as the Karlin-Altschul statistics that are a key part of BLAST, arguably the most successful piece of computational biology software of all time.

For 3 Nobel Winners, a Molecular Mystery Solved

http://www.nytimes.com/2013/10/08/health/3-win-joint-nobel-prize-in-medicine.html?hp&_r=0

Three Americans won the Nobel Prize in Physiology or Medicine on Monday for discovering the machinery that regulates how cells transport major molecules in a cargo system that delivers them to the right place at the right time.

The Karolinska Institute in Stockholm announced the winners: James E. Rothman, 62, of Yale University; Randy W. Schekman, 64, of the University of California, Berkeley; and Dr. Thomas C. Südhof, 57, of Stanford University. Their basic research solved the mystery of how cells, which are factories producing molecules, organize a system to transport the molecules within cells and export them outside.