http://www.synapse2disease.ca/en_projet.html
The Synapse to Disease (S2D) project was initiated in 2006, following a successful funding application to Genome Canada and Genome Quebec. The original aim of the S2D project was to identify synaptic genes that cause or predispose an individual to neurodevelopmental diseases such as autism, mental retardation, schizophrenia, and Tourette Syndrome. Contrary to single-gene diseases such as Huntington or Duchenne Muscular Dystrophy, the diseases selected for S2D project result from the interaction of multiple genetic factors (genes) and environmental factors. They are therefore classified as "complex", and represent a major challenge for genetic analysis.
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