Avoid USB device from getting disconnected automatically
http://www.sevenforums.com/hardware-devices/53445-usb-hard-drive-keeps-disconnecting-disappearing.html
in the device manager (Control Panel > System > Hardware) go to USB root hub properties and disable power
management for the hub it will power down USB to save power
Saturday, May 12, 2012
Thursday, May 10, 2012
Spreading happiness
"Resolve
to make at least one person happy every day, and then in ten years you
may have made three thousand, six hundred and fifty persons happy, or
brightened a small town by your contribution to the fund of general
enjoyment."
--Sydney Smith
... assuming you meet one new person everyday
--Sydney Smith
... assuming you meet one new person everyday
Tuesday, May 8, 2012
1000 genomes on Amazon's cloud
http://www.nature.com/nbt/journal/v30/n5/full/nbt0512-376.html?WT.ec_id=NBT-201205
The world's largest data set on human genetic variation, the 1000 Genomes Project, is now available for free through Amazon Web Services.
The 1000 Genomes Project is an international effort initiated in 2008 to collect the genomes of more than 2,600 people from 26 populations around the world (Nat. Biotechnol. 26, 256, 2008).
The world's largest data set on human genetic variation, the 1000 Genomes Project, is now available for free through Amazon Web Services.
The 1000 Genomes Project is an international effort initiated in 2008 to collect the genomes of more than 2,600 people from 26 populations around the world (Nat. Biotechnol. 26, 256, 2008).
Human brain shaped by duplicate genes
http://www.nature.com/news/human-brain-shaped-by-duplicate-genes-1.10584?WT.ec_id=NEWS-20120508
James Sikela, an evolutionary geneticist at the University of Colorado, Denver, adds that the SRGAP2 duplications are likely to be one of a multitude of genetic changes that moulded the human brain.
James Sikela, an evolutionary geneticist at the University of Colorado, Denver, adds that the SRGAP2 duplications are likely to be one of a multitude of genetic changes that moulded the human brain.
Monday, May 7, 2012
Saturday, May 5, 2012
NVidia GeForce 8400 GS Video Card
http://www.tomshardware.com/forum/652-63-window-monitor-1680x1050-1920x1080-resolution-here
http://forums.nvidia.com/index.php?showtopic=21993&st=20
1. NVIDIA Control Panel > Display > Manage custom timings.
2. Click both "Treat as HDTV" and "Allow modes not exposed by the display"
3. Click [Create...]
4. Under Custom display mode values:
Horizontal desktop pixels: 1440
Vertical desktop lines: 900
GDI Refresh rate: 60
Bits per pixel: 32
(don't have "Interlaced" checked)
5. Click [Advanced >>] (by the way this is where I didn't go when NVIDIA emailed me)
6. Under "Back-end parameters":
Timing standard: DMT
Desired refresh rate: 60
(the rest of the fields are grayed out)
7. Under "Front-end paramers"
Scaling type: Display (none)
8. Click [Test]
9. Click [OK]
Beta driver fix for not being able to save custom resolution
http://www.nvidia.com/object/win7-winvista-64bit-301.24-beta-driver.html
http://forums.nvidia.com/index.php?showtopic=189757
Use version 258.96?
http://www.tomshardware.com/forum/54194-3-resolution-higher-native
"LCDs cannot go beyond native resolution. It is phyiscally impossible since due to the specific number of pixel.
What might be happening is the resolution is being down converted back to native resolution or it sets the "usable" desktop space to 1920 x 1080 (or whatever), but only 1440 x 900 is displayed at a time. You would need to scroll to view the rest of the "usable" desktop space." -- works for CRTs though ...
http://answers.yahoo.com/question/index?qid=20070901023705AArlQAA
*Your monitor, Model : L196WTQ-BF is the finest 19" currently offered by LG and your NVidia does not even warm up to do this.
MONITOR:
The LG is a great 19" and 1440 x 900 is not stressing it at all. This is the "Native" resolution which means 1440 x 900 is the "optimum" or "perfect" resolution setting for this monitor. Contrary to popular belief, the maximum resolution can be configured considerably higher. With a bit of tweaking my 19" wide LCD and NVidia GeForce-256 displays 1920 x 1200 just fine. Also, using the 32bit color depth setting actually displays the monitor’s max of 24bit.
http://forums.nvidia.com/index.php?showtopic=21993&st=20
1. NVIDIA Control Panel > Display > Manage custom timings.
2. Click both "Treat as HDTV" and "Allow modes not exposed by the display"
3. Click [Create...]
4. Under Custom display mode values:
Horizontal desktop pixels: 1440
Vertical desktop lines: 900
GDI Refresh rate: 60
Bits per pixel: 32
(don't have "Interlaced" checked)
5. Click [Advanced >>] (by the way this is where I didn't go when NVIDIA emailed me)
6. Under "Back-end parameters":
Timing standard: DMT
Desired refresh rate: 60
(the rest of the fields are grayed out)
7. Under "Front-end paramers"
Scaling type: Display (none)
8. Click [Test]
9. Click [OK]
Beta driver fix for not being able to save custom resolution
http://www.nvidia.com/object/win7-winvista-64bit-301.24-beta-driver.html
http://forums.nvidia.com/index.php?showtopic=189757
Use version 258.96?
http://www.tomshardware.com/forum/54194-3-resolution-higher-native
"LCDs cannot go beyond native resolution. It is phyiscally impossible since due to the specific number of pixel.
What might be happening is the resolution is being down converted back to native resolution or it sets the "usable" desktop space to 1920 x 1080 (or whatever), but only 1440 x 900 is displayed at a time. You would need to scroll to view the rest of the "usable" desktop space." -- works for CRTs though ...
http://answers.yahoo.com/question/index?qid=20070901023705AArlQAA
*Your monitor, Model : L196WTQ-BF is the finest 19" currently offered by LG and your NVidia does not even warm up to do this.
MONITOR:
The LG is a great 19" and 1440 x 900 is not stressing it at all. This is the "Native" resolution which means 1440 x 900 is the "optimum" or "perfect" resolution setting for this monitor. Contrary to popular belief, the maximum resolution can be configured considerably higher. With a bit of tweaking my 19" wide LCD and NVidia GeForce-256 displays 1920 x 1200 just fine. Also, using the 32bit color depth setting actually displays the monitor’s max of 24bit.
Thursday, May 3, 2012
Picasa - Google photo editing
http://www.ubuntugeek.com/howto-install-picasa-3-5-in-ubuntu.html
Picasa is a software application for organizing and editing digital photos, originally created by Idealab and owned by Google since 2004.”Picasa” is a blend of the name of Spanish painter Pablo Picasso, the phrase mi casa for “my house” and “pic” for pictures (personalized art).
Picasa is a software application for organizing and editing digital photos, originally created by Idealab and owned by Google since 2004.”Picasa” is a blend of the name of Spanish painter Pablo Picasso, the phrase mi casa for “my house” and “pic” for pictures (personalized art).
Wednesday, May 2, 2012
Genomic Analysis of Reactive Astrogliosis
http://www.jneurosci.org/content/32/18/6391.abstract
Reactive astrogliosis is characterized by a profound change in astrocyte phenotype in response to all CNS injuries and diseases. To better understand the reactive astrocyte state, we used Affymetrix GeneChip arrays to profile gene expression in populations of reactive astrocytes isolated at various time points after induction using two mouse injury models, ischemic stroke and neuroinflammation. We find reactive gliosis consists of a rapid, but quickly attenuated, induction of gene expression after insult and identify induced Lcn2 and Serpina3n as strong markers of reactive astrocytes. Strikingly, reactive astrocyte phenotype strongly depended on the type of inducing injury. Although there is a core set of genes that is upregulated in reactive astrocytes from both injury models, at least 50% of the altered gene expression is specific to a given injury type. Reactive astrocytes in ischemia exhibited a molecular phenotype that suggests that they may be beneficial or protective, whereas reactive astrocytes induced by LPS exhibited a phenotype that suggests that they may be detrimental. These findings demonstrate that, despite well established commonalities, astrocyte reactive gliosis is a highly heterogeneous state in which astrocyte activities are altered to respond to the specific injury. This raises the question of how many subtypes of reactive astrocytes exist. Our findings provide transcriptome databases for two subtypes of reactive astrocytes that will be highly useful in generating new and testable hypotheses of their function, as well as for providing new markers to detect different types of reactive astrocytes in human neurological diseases.
Reactive astrogliosis is characterized by a profound change in astrocyte phenotype in response to all CNS injuries and diseases. To better understand the reactive astrocyte state, we used Affymetrix GeneChip arrays to profile gene expression in populations of reactive astrocytes isolated at various time points after induction using two mouse injury models, ischemic stroke and neuroinflammation. We find reactive gliosis consists of a rapid, but quickly attenuated, induction of gene expression after insult and identify induced Lcn2 and Serpina3n as strong markers of reactive astrocytes. Strikingly, reactive astrocyte phenotype strongly depended on the type of inducing injury. Although there is a core set of genes that is upregulated in reactive astrocytes from both injury models, at least 50% of the altered gene expression is specific to a given injury type. Reactive astrocytes in ischemia exhibited a molecular phenotype that suggests that they may be beneficial or protective, whereas reactive astrocytes induced by LPS exhibited a phenotype that suggests that they may be detrimental. These findings demonstrate that, despite well established commonalities, astrocyte reactive gliosis is a highly heterogeneous state in which astrocyte activities are altered to respond to the specific injury. This raises the question of how many subtypes of reactive astrocytes exist. Our findings provide transcriptome databases for two subtypes of reactive astrocytes that will be highly useful in generating new and testable hypotheses of their function, as well as for providing new markers to detect different types of reactive astrocytes in human neurological diseases.
mitochondrial function to cancer cell metabolism
http://www.nature.com/nrc/posters/mitochondria/index.html
http://www.nature.com/nrc/posters/mitochondria/mito_poster.pdf
However, mitochondria also have their own DNA and mutations in mitochondrial genes are common and have been shown to be involved in human diseases, such as mitochondrial myopathy.
This poster, covers our current understanding of the contribution of mitochondrial function to cancer cell metabolism.
http://www.nature.com/nrc/posters/mitochondria/mito_poster.pdf
However, mitochondria also have their own DNA and mutations in mitochondrial genes are common and have been shown to be involved in human diseases, such as mitochondrial myopathy.
This poster, covers our current understanding of the contribution of mitochondrial function to cancer cell metabolism.
Controversial research: Good science bad science
http://www.nature.com/news/controversial-research-good-science-bad-science-1.10511?WT.ec_id=NEWS-20120501
Nuclear fuel or nuclear weapons?
Brain scanning or Big Brother?
Climate saviour or climate disaster?
Baby blessing or Brave New World?
Nuclear fuel or nuclear weapons?
Brain scanning or Big Brother?
Climate saviour or climate disaster?
Baby blessing or Brave New World?
Open data
http://www.nature.com/news/open-data-project-aims-to-ease-the-way-for-genomic-research-1.10507?WT.ec_id=NEWS-20120501
Last summer, biologist Andrew Kasarskis was eager to help decipher the genetic origin of the Escherichia coli strain that infected roughly 4,000 people in Germany between May and July. But he knew it that might take days for the lawyers at his company — Pacific Biosciences of Menlo Park, California — to parse the agreements governing how his team could use data collected on the strain. Luckily, one team had released its data under a Creative Commons licence that allowed free use of the data, allowing Kasarskis and his colleagues to join the international research effort and publish their work1 without wasting time on legal wrangling.
The Portable Legal Consent will initially deliver data to Synapse, a computational research environment developed by Sage Bionetworks, a non-profit biomedical research organization based in Seattle, Washington. But the project is also developing tools that will allow researchers outside of Synapse to tap into its databases. The project, part of a groundswell of new consumer- and patient-driven models for conducting science2, approaches consent in a different way to many genomic studies, by informing donors that it is not possible to guarantee full anonymity of their data, not tying the data to specific studies, and asking researchers to respect broad terms of use — by not attempting to identify data contributors and not sharing the data with others who don't agree to the same terms, for example.
Last summer, biologist Andrew Kasarskis was eager to help decipher the genetic origin of the Escherichia coli strain that infected roughly 4,000 people in Germany between May and July. But he knew it that might take days for the lawyers at his company — Pacific Biosciences of Menlo Park, California — to parse the agreements governing how his team could use data collected on the strain. Luckily, one team had released its data under a Creative Commons licence that allowed free use of the data, allowing Kasarskis and his colleagues to join the international research effort and publish their work1 without wasting time on legal wrangling.
The Portable Legal Consent will initially deliver data to Synapse, a computational research environment developed by Sage Bionetworks, a non-profit biomedical research organization based in Seattle, Washington. But the project is also developing tools that will allow researchers outside of Synapse to tap into its databases. The project, part of a groundswell of new consumer- and patient-driven models for conducting science2, approaches consent in a different way to many genomic studies, by informing donors that it is not possible to guarantee full anonymity of their data, not tying the data to specific studies, and asking researchers to respect broad terms of use — by not attempting to identify data contributors and not sharing the data with others who don't agree to the same terms, for example.
Love vs Power
"Where
love rules, there is no will to power; and where power predominates,
there love is lacking. The one is the shadow of the other."
--Carl Jung
--Carl Jung
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