Bioinformatics tools

http://guides.uflib.ufl.edu/content.php?pid=13898&sid=93373

http://www.oxfordjournals.org/nar/database/c/

http://bioinformatics.ca/links_directory/

Inferring cancer subnetwork markers using density-constrained biclustering

http://bioinformatics.oxfordjournals.org/content/26/18/i625.abstract


Phuong Dao*, Recep Colak*, Raheleh Salari, Flavia Moser, Elai Davicioni, Alexander Schonhuth**, Martin Ester**
9th European Conference on Computational Biology (ECCB 2010)
Also: Bioinformatics 26(13): 1608-1615 (2010)
* Joint first authorship, **Corresponding author

Abstract

Motivation: Recent genomic studies have confirmed that cancer is of utmost phenotypical complexity, varying greatly in terms of subtypes and evolutionary stages. When classifying cancer tissue samples, subnetwork marker approaches have proven to be superior over single gene marker approaches, most importantly in cross-platform evaluation schemes. However, prior subnetwork-based approaches do not explicitly address the great phenotypical complexity of cancer.

Results: We explicitly address this and employ density-constrained biclustering to compute subnetwork markers, which reflect pathways being dysregulated in many, but not necessarily all samples under consideration. In breast cancer we achieve substantial improvements over all cross-platform applicable approaches when predicting TP53 mutation status in a well-established non-cross-platform setting. In colon cancer, we raise prediction accuracy in the most difficult instances from 87% to 93% for cancer versus non−cancer and from 83% to (astonishing) 92%, for with versus without liver metastasis, in well-established cross-platform evaluation schemes.

Availability: Software is available on request.

Contact: alexsch@math.berkeley.edu; ester@cs.sfu.ca

Supplementary information: Supplementary data are available at Bioinformatics online.

ENCODE downloads

http://genome.ucsc.edu/ENCODE/downloads.html

10 Tips for how to get the most from your PhD. -- fejes

http://blog.fejes.ca/2011/07/24/10-tips-for-how-to-get-the-most-from-your-phd/

1. Say yes, until you learn to say no.
2. Learn to communicate.
2b. Learn to teach.
3. Take advantage of your university’s resources.
4. Meet your future life partner.
4b. Make some great friends.
5. Decide what you stand for, and stand for it.
6. Keep good notes
7. Be a sponge.
8. Face the challenges.
9. Don’t give up.
10. Enjoy the ride.

Warring States 2011

http://www.imdb.com/title/tt1885448/

Bioinformatics analysis of microarray data.

http://www.ncbi.nlm.nih.gov/pubmed/19763933

Methods Mol Biol. 2009;573:259-84.
Bioinformatics analysis of microarray data.
Zhang Y, Szustakowski J, Schinke M.
Source

Novartis Institutes for BioMedical Research, Cambridge, MA, USA.

Project Nim, Rise of the Apes - chimps

http://www.ft.com/cms/s/2/89b06dac-c3fb-11e0-b302-00144feabdc0.html#axzz1UkH7Z3c8

Bear Mountain

http://www.trailpeak.com/trail-Bear-Mountain-near-Hope-Airport-BC-462

A 1.5hour(150km) drive East of Vancouver,
just past the Village of Harrison Hot Springs.


Round Trip 19km,11.8miles.
Elevation Gain 1010meters,3315feet
Average grade 10.6%
Book says 'Allow 6-hours'


www.vancouvertrails.com/

Team building activities

http://www.teamtechnology.co.uk/team-building-activities-outdoors.html

http://www.eventus.co.uk/outdoor.asp

http://www.singaporeteambuilding.com/teambuilding/

Ultimate Frisbee

Amazing Race

# Rocket Building
You construct a water-powered rocket, and the team that sends their rocket the furthest wins.

# Bridge building
The team have to get from one side of a beach or lawn to another, using only the pieces of wood provided. and without them or the wood touching the ground. Requires good planning and balance.

100 minus 1 day

"If you live to be 100, I hope I live to be 100 minus 1 day, so I never have to live without you."



Winnie the Pooh

Confident people.

10 things you can do right now to improve your chances for a promotion
Beth Braccio Hering, Special to CareerBuilder

Hurzeler claims that confidence level is the first thing he notices when someone enters his office. He also claims that most confident people are faking it. "They are just as scared of the world as the next person, but they have learned to push that fear into the background so they can reach over their heads and pull themselves up. Confident people are willing to explore, to lead, to speak up, to try new things, to innovate, to fail and to get up off the ground and try again."

"Winners know who the players are in the company and throughout the whole industry. They work to understand it all so that someday they can run it all."

http://www.careerbuilder.ca/Article/CB-805-Workplace-Issues-10-things-you-can-do-right-now-to-improve-your-chances-for-a-promotion/?sc_extcmp=cbca_9805&cblang=CAEnglish&SiteId=cbca_9805

Google+ Hangout

http://gadgetwise.blogs.nytimes.com/2011/07/05/is-googles-hangouts-its-killer-app/

But it wasn’t just any chatroom. It was a virtual “hangout,”

An Uber-comparison of RDFa, Microdata and Microformats

http://manu.sporny.org/2011/uber-comparison-rdfa-md-uf/