Friday, February 5, 2010

terms

Mechanism involves weakening of the cell walls of the surrounding seed tissues,
especially at the micropylar region

Pectin methylesterase (PME) is a cell wall hydrolase involved in mediating
weakening of the cell walls of the megagametophyte of yellow-cedar

Acidic environment (due to IAA (auxin)) of cell wall ph7 activates Expansin which loosens cell wall by breaking down hemicellulose

In Arabidopsis:
Efflux carriers
PIN gene-family of eight
Influx carriers
AUX gene-family of four

Latest Japanese Songs 2010

http://www.onlylyrics.com/gr_new.php?gid=16

Latest Japanese Songs 2010 Video
"Kagayaku Hito"
Angela Aki
"Ryuusei No Namida"
Chiaki Kuriyama
"Real Force"
Elisa
"Keshin"
12012
"This Is Not A Game"
Jasmine
"The Love Songs"
Spontania
"Memory"
Lil’b
"Kaeru Basho"
Thelma Aoyama
"Bye Bye"
Beni
"Keropak"
Ayaka Hirahara
"Troublemaker"
Arashi
"Soba Ni Ite Sugu Kiete."
Yu-A
"Now!"
Satomi Takasugi
"Sakurairo"
Satomi Takasugi
"Far Away"
Nana Tanimura
"Believe You"
Nana Tanimura
"Sakura"
Monkey Majik
"Eien Yori Nagaku"
Mai Kuraki
"Hitomi No Screen"
Hey! Say! Jump
"Speak Out!!"
Michi
"Gift"
Bahashishi
"Distance"
Bahashishi
"Nostalgia"
Ikimono Gakari
"Yawarakana Cycle"
Chitose Hajime
"Kono Michi"
Aoi Teshima
"Love Or Lies"
Capsule
"Heaven"
Coma-Chi
"Dreamer"
Sunmin
"Lucky Star"
Ai Otsuka
"Bless"
L´arc~en~ciel
"Gachizakura"
Shonannokaze
"After Laughter"
School Food Punishment
"Future Nova"
School Food Punishment
"Best Friend"
Kana Nishino
"Lastica"
Karasu
"Let’s Go Higher"
Ryohei
"Luna Regalo ~tsuki Kara No Okurimono~"
Minami Kizuki
"Hanbunko"
Stereopony
"Like Yesterday"
Brilliant Green
"Kimi Ni Deaete Yokatta"
Metis
"Deep"
Exile
"S.H.E."
Juju
"Last Kiss"
Juju
"Sakura Ame"
Juju
"Love Yourself -Kimi Ga Kirai Na Kimi Ga Suki-"
Kat-Tun
"Change Myself"
Iconiq
"Itsu No Hi Mo"
Mao Abe
"Morning Glory"
Bonnie Pink
"Otakebi Boy Wao!"
Berryz Koubou
"Tomodachi Wa Tomodachi Nanda!"
Berryz Koubou
"Tsukishirube"
Yuuka Nanri
"Ureshikutte Daki Au Yo"
Yuki
"Fuwafuwa"
Yui Makino
"Fuyumeku"
Yo Hitoto
"Sports"
Tokyo Jihen
"Mata Asa Ga Kuru"
Tokio
"Advance"
Tokio
"Sleep"
Sid
"Forever Love (shota X Miliyah)"
Shota Shimizu
"Owari To Hajimari"
Seamo
"Lost Boy"
Seamo
"Shunkan Sentimental"
Scandal
"Lonely Lonely Lonely"
Saori@Destiny
"Atarashii Yes"
Salyu
"Dance For Me"
Ryohei
"Hitomi No Oku Wo Nozokasete"
Porno Graffitti
"Kanzen Kankaku Dreamer"
One Ok Rock
"Silent Bible"
Nana Mizuki
"Omoide Ni Naru No?"
Nami Tamaki
"Onna Ga Medatte Naze Ikenai"
Morning Musume
"Love Letter"
Mihimaru Gt
"Ichiban Hoshi"
Mai Hoshimura
"Ready For Love"
Juju
"L.O.V.E"
Home Made Kazoku
"Hatsukoi"
Hanako Oku
"Change"
Every Little Thing
"Our Songs"
Buono!
"Dokudanjou Beauty"
Buck-Tick
"For You"
Azu
"Modorenai Ashita"
Aiko
"Tattoo"
12012
"Butterfly City"
Zeebra Feat. Ryo The Sky Walker & Mummy-D
"Dakishimete"
Ryuichi Kawamura
"Fall In Love"
Thelma Aoyama Feat. Sol From Bigbang
"Makemagic"
Jealkb
"Voice ~tadoritsuku Basho~"
Sachi Tainaka
"Someday ~watashi Wo Wasurete~"
Yumi Shizukusa
"Fate Seeker"
M.O.V.E
"Kimi Ga Inai Mirai"
Do As Infinity
"Girls Be Ambitious"
Haruka Tomatsu
"Always"
Mika Nakashima
"Gloria"
Yui
"Ai"
Motohiro Hata
"Ehagaki No Haru"
Aqua Timez
"Toki No Mukou Maboroshi No Sora"
Fictionjunction
"Sailing My Life"
Ayaka Hirahara
"Sign"
Beni
"Period"
Chemistry
"Rodeo Star Mate"
Pillows
"Endless Night"
Halcali

Thursday, February 4, 2010

Auxin - an essential growth hormone

Auxin:
- pattern formation
- elongation
- required for viability like cytokinins
- synthesized at the tips of young leaves
- promotes apical (height) dominance
- prevents leaf abscission (loss)
- promotes fruit development
- generation when cut is made
- promote seedless fruits
- herbicides in dicot

Biosynthesis
- use Trp as precursor
- controlled by conjugation (add methyls to convert it to storage forms)

All auxins: Aromatic ring + carboxyl group (0.5nm separation)
eg. IAA - Indole-3-acetic acid

* phototropism (coleoptile curvature test) - differential growth

Auxing Transport
- Basipetal (shoot to root) shift in auxin production
- polar transport from shoot tip (apex) to root tip (base)
- experiment is the donor block of IAA, no IAA obtained in donor when shoot was reversed
- inside of cell is pH 7.2 (more basic than outside pH 5)
- ~ 50% IAA is protonated & can diffuse down a conc. gradient
- ~ 50% is charged (IAA-) and enters via a 2H+/IAA- symporter (influx carrier) (encoded by AUX1 gene)
- IAA- exits cell via efflux carriers (encoded by PIN1 gene) (only found at the basal end of the cells) -> polar transport
- IAA- helps with H+ extrusion: 1. helps in H+-ATPase gene expression 2. membrane trafficking 3. stabilize H+-ATPase stabilization

ABA

Interactions between ABA and other hormones that are antagonistic to ABA


Abscisic Acid hormone
- controls seedling's vigour
- promotes reserve synthesis and late-embryogenesis abundant (LEA) proteins (for the protection of water stress)
- accumulation of dessication protectants
- promotes seed dormancy
- inhibit precocious germination (vivipary)

Evidence
1) embryo culture - addition of ABA inhibit germination and promoted reserve deposition
2) vivipary - Red mangrove reduced sensitivity to high [ABA]
3) preharvesting - germination on parent plant prior to harvesting, eg. cereals, again, insensitive to high [ABA]

*NOTE: sprouting susceptible - they like to sprout no matter what so insensitive to ABA, transcription factor decreased at maturity, eg. cereals
sprouting resistant - don't want to sprout so SENSITIVE to ABA, ABI3/VPI1 transcription factor levels maintained throughout

Lec 4
response mutants - insensitivity to ABA, defective ABA signaling pathway
e.g. vp1 (all lowercase when naming mutants, all upper case when naming GENES, eg. VP1 gene) in maize, abi3 in arabidopsis (green, less dormant, less reserve, dessication/drying-intolerant, matures prematurely)

ABI3/VP1 genes are transcription factors, binds with FUS3, LEC1 transcription factors and they all bind to RY cis promoter to control maturation

ABRE - ABA-ResponsiveElements (promoter element, sequence in genes)

ABA/GA ratio (ABA - sleep pill and GA - wake up pill are antagonistic)
These GAs induce a developmental program that leads to vivipary
in the absence of normal amounts of ABA

A reduction of GAs re-establishes an ABA/GA ratio appropriate for suppression
of germination and induction of maturation.

Mod 6, 7
Sprouting leads to damage due to premature hydrolysis of grain reserves –
hydrolytic enzymes associated with post-germinative reserve mobilization
degrade starch & protein of grain

When malting process is terminated, malted grain consists of
friable endosperm containing:
High amounts of enzymes, e.g. α-amylase, which will later
participate in the hydrolysis of the starch to produce sugars
for fermentation
Altered protein & various other chemicals (quality of final product)
Pre-harvest sprouted grain is unacceptable to the malting industry!

5th Canadian Student Conference on Biomedical Computing and Engineering

5th Canadian Student Conference
on Biomedical Computing and Engineering
http://www.cs.uwaterloo.ca/conferences/cscbce2010/

Conference topics include (but are not limited to):
Computational Biology and Bioinformatics

Medical Imaging and Computer-Aided Procedures
• Computational Genomics
• Molecular sequence analysis
• Molecular evolution
• Protein structures
• Gene networks
• Combinatorial libraries and drug design
• Computational Proteomics
• Microarray design and data analysis
• Structural and functional genomics
• Biomedical data/text mining
• Integrative/comparative genomics
• Applications of the above

• Medical image segmentation
• Medical image registration
• Image based tissue classification
• Computer aided diagnosis
• Visualization methods
• Computer assisted interventional systems
• Anatomical atlases
• New applications for specific imaging systems
• Functional imaging
• Biological image analysis
• Applications of the above


Important Dates
Paper submission deadline: Jan 16, 2010 March 15, 2010 (23:59 EST) (FINAL)
Paper notification: Mar 28, 2010
Camera ready version: Apr 10, 2010

Download the call for papers [pdf] - [txt]

metagenomics

Identifying biologically relevant differences between metagenomic communities
Donovan H. Parks 1 and Robert G. Beiko 1,*

1Faculty of Computer Science, Dalhousie University, 6050 University Avenue, Halifax, Nova Scotia, Canada B3H 1W5
http://bioinformatics.oxfordjournals.org/cgi/content/abstract/btq041v1?etoc
Availability: Python source code and binaries are freely available from our web-site at: http://kiwi.cs.dal.ca/Software/STAMP

Wednesday, February 3, 2010

Bioinformatics / Data science Jobs

keywords: bioinformatician, scientific programmer, computational scientist, computational biologist, data analyst, research associate

Bioinformatics Centre for Computational Medicine (CCM), SickKids, Toronto
Michael Brudno
http://ccm.sickkids.ca/?q=node/32

Top 100 Tech Companies
http://www.biv.com/article/20130507/BIV050103/130509961/-1/BIV/top-100-tech-companies-in-bc-in-2013

Telus Health
http://www.telushealth.com/careers

Princess Margaret Cancer Centre, University Health Network
http://pmgenomics.ca/hoffmanlab/join/#programmer

IRIC, Universite de Montreal
Bioinformatics platform, Institute for Research in Immunology and Cancer (IRIC)
Université de Montréal, Montréal, QC
http://bioinformatics.ca/node/18036 
 
Ryerson University
www.ryerson.ca/‎

http://www.biotalent.ca

Pulse Energy
http://www.pulseenergy.com/

HSSBC
Health Shared Services BC
http://www.brainhunter.com/frontoffice/seekerViewJobDetailAction.do?sitecode=pl559&jobId=1853459&page=search&external=

Telus Health
http://www.telushealth.com/careers

Memorial Sloan-Kettering Cancer Center  (New York)
http://careers.mskcc.org/careers/job-search.asp

Invitae (San Francisco, California)
http://invitae.com/main/careers/

Sorin Group
http://lifesciencesbc.ca/job-board/jobs/Sorin-Group-Canada-Inc._2013-04-05_155954.aspx

http://genetrack.com/

http://compbio.sph.harvard.edu/chb/articles/chb-is-hiring-again
http://www.hsci.harvard.edu/research/center-stem-cell-bioinformatics
http://compbio.sph.harvard.edu/chb/

bcjobs.ca


Dr R.E.W. (Bob) Hancock, OC, OBC, FRSC,  (Immunology)

BC Technology Industry Association
http://www.bctia.org/Resources/BC-Tech-Jobs

PROOF Center of Excellence (UBC)
http://www.proofcentre.ca/careers/

Allon Therapeutics Inc. - biotech central nervous system therapies
http://www.allontherapeutics.com/corporate/careers/

IDSIA (Istituto Dalle Molle di Studi sull'Intelligenza Artificiale) is a non-profit oriented research institute for artificial intelligence, affiliated with both the Faculty of Informatics of the University of Lugano and the Department of Innovative Technologies of SUPSI, the University of Applied Sciences of Southern Switzerland.
www.idsia.ch

GE HealthCare
http://www.forbes.com/sites/skollworldforum/2013/08/09/how-ge-healthcare-is-solving-the-worlds-most-complex-rural-health-challenges/

Government Federal Student Work Experience Program (FSWEP)
http://jobs-emplois.gc.ca/centres/presentation/read-lire-eng.htm

Centre for Drug Research and Development, UBC
http://www.cdrd.ca/current-opportunities

Hospital for Sick Children (SickKids), affiliated with the University of Toronto,
http://www.sickkids.ca/Research/index.html

http://www.cbse.ucsc.edu/jobs/staff#biodata_eng

http://www.calmis.ca.gov/file/biotech/bio-bioinformatics-specialists.pdf
http://www.sciencebuddies.org/science-fair-projects/science-engineering-careers/Genom_bioinformaticsscientist_c001.shtml

https://www.canadas50best.com/en/Pages/Home.aspx

nus.edu.sg University of Singapore, Division of Bioengineering


http://www.canadastop100.com/bc/

mailto:career@rescan.com

http://www.knome.com/

http://www.iprogen.com/

http://www.oncogenex.ca/

http://wwwext.amgen.com/careers/overview.html
http://www.dowagro.com/careers/
http://www.hr.umaryland.edu/

bioinformatician, computational biologist, software programmer, scientist

 http://www.scientistsolutions.com/t4370-jobs+for+freshers+in+bioinfo.html
http://bioinformatics.org/jobs/
http://www.bioplanet.com/
http://aaas.sciencecareers.org/js.php?q=bioinformatics
http://jobs.biohealthmatics.com/Jobs/Bioinformatics/
http://www.nature.com/naturejobs/index.html
http://www.newscientistjobs.com/jobs/default.aspx
http://biointelligence.wordpress.com/tag/bioinformatics-companies/
http://www.bioinformaticsdirectory.com/
http://www.mdblackbox.com/

RIM
https://rim.taleo.net/careersection/professional/profile.ftl?lang=en&alt=1

Microsoft
https://careers.microsoft.com/AppliedJobs.aspx

Government of Canada: Health

Student Biotechnology Network

BCIT

Google
https://www.google.com/jobs/application/submitApplicant
http://www.google.com/jobs/students/us/internships/eng/software-engineering-intern-summer-2010-north-america-locations/index.html

Amazon
http://www.amazon.com/Apply-Careers-Homepage/b?ie=UTF8&node=239363011

SAP - Business Objects
http://www.sap.com/canada/careers/index.epx

J. Craig Venter
https://careers.jcvi.org/careers/

Fred Hutchinson Cancer Research Center
http://www.fhcrc.org/about/jobs/index.html

Xenon
http://www.xenon-pharma.com/pages/careers.php

Zymeworks
http://zymeworks.com/

Worldwide career jobs
http://online.usacareerguides.com

Dow Agro Sciences
https://dow.taleo.net/careersection/10060/joblist.ftl
http://www.careerbuilder.com/JobSeeker/Jobs/JobResults.aspx?ncc=^%22DOW+AGRO+SCIENCES%22%24&cbRecursionCnt=1&cbsid=fd9fdedd5b774932ad389145fd623a8d-320876531-w9-6&ns_siteid=ns_ca_g_Bioinformatician_-_Di_

CareerBuilder
http://www.careerbuilder.com

Prostate Cancer at VGH
http://www.prostatecentre.com/aboutus/aboutus.php?pageID=12

Bioinformatics.ca
http://www.bioinformatics.ca/resources/jobs

http://www.thesciencejobs.com/category/jobs/biology/bioinformatics/page/2

Public Health Services Authority
http://careers.phsa.ca/CareerCentre/CareerOpportunties/default.htm

Canadian Life Sciences
http://www.canadianlifesciences.com/ca/db/index.php

lifesciencesbc
http://www.lifesciencesbc.ca/Employment/
http://www.lifesciencesbc.ca/Members/Member_Company_Profiles/Members_by_Sector2.asp

Startup companies
http://www.grants-loans.org/
http://www.canadabusiness.ca/eng/82/

Information interview
- ask about companies, what they do etc. leave resume

Craiglist
http://vancouver.en.craigslist.ca/van/sof/

UBC Bioinformatics Programmer
http://www.hr.ubc.ca/careers/staff_postings.html

Public Health Agency Canada
http://www.phac-aspc.gc.ca/php-psp/career-eng.php
Public Health Agency: FA10 - Bioinformatics Research Technician

St. Paul's Hospital - iCAPTURE / James Hogg Research Centre
http://www.icapture.ubc.ca/opp/opp_emp.shtml

Genome Sciences Centre
http://www.bcgsc.ca/career/
http://www.bcgsc.ca/career/CBBAG-10-03-25/job_view

Centre for Drug Research and Development
www.cdrd.ca/

StemCell
http://www.stemcell.com/

BC Cancer Agency
http://www.bccancer.bc.ca/default.htm

UBC Networks of Centres of Excellence / Michael Smith Labs
http://www.maps.ubc.ca/PROD/index_detail.php?locat1=081-2

Tekmira Pharmaceuticals - RNA interference therapeutics
http://www.tekmirapharm.com/Careers/Careers.asp

Co-op Bioinformatics Research Technician (4 mths - Fall 10)
Public Health Agency of Canada, Lethbridge, Alberta
Supervisor: Dr. Eduardo Taboada
Address your cover letter to Dr. Taboada

Vancouver Prostate Cancer Center
http://www.prostatecentre.com/about-us/partners

Sanger -
Senior Ensembl Web Developer - DAS Support
https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=111984

Pfizer - Professional (P2) Bioinformatics Developer
https://jobs.pfizer.com/psc/recruit/EMPLOYEE/HRMS/c/LSYS_DEVELOPMENT.Z_PFIZER_JOBS.GBL?PostingID=85440

BioTalent Canada
http://www.biotalent.ca

BioDiscovery - NEXUS - Copy Number Variation
http://www.biodiscovery.com/index/employment

Novartis
http://www.gnf.org/careers/job_2010122224353.htm

Tempest Development Group - Gov't Apps
http://www.tempestdg.com/

accelrys
http://accelrys.com/about/careers/us.html

GenomeDX
www.genomedx.com/

University of Calgary
http://www.ucalgary.ca/bmb/

Alberta Children's Hospital
http://research4kids.ucalgary.ca/

Boreal Genomics
http://www.borealgenomics.com/ 

StarFish Medical
http://starfishmedical.com/index.php/careers/

Harvard University ASPIRE
https://sjobs.brassring.com/1033/ASP/TG/cim_home.asp?partnerid=25240&siteid=5341

BioGPS
http://biogps.blogspot.com/2011/01/recruiting-for-postdoc-in.html

Softgenetics
http://www.softgenetics.com/

CMMT
http://www.cmmt.ubc.ca/getinvolved/careers

Brain Research, UBC
http://www.brain.ubc.ca/jobsoverview/volunteer_positions.htm

Genomatix
http://www.genomatix.de/en/index.html

CFRI training / career searching
http://www.cfri-training.ca/student/trainee_resources.asp

RCMP/Government

Center of Applied Genomics, Unniversity of Pennsylvania, Philadelphia
http://www.research.chop.edu/programs/cag/

The Genome Analysis Centre--Norwich, UK
http://www.tgac.bbsrc.ac.uk/

Sandelin group, University of Copenhagen, Bioinformatics Group
http://people.binf.ku.dk/albin/

http://www.getbioinformaticsjobs.com

http://www.medbiogene.com/

http://www.health2media.com/about/about.html

http://bioinformatics.ca/resources/jobs

http://www.sequilab.org/pages/home.jsf

http://www.alleninstitute.org/about_us/careers.html

http://cardiome.com/wordpress/?cat=8

http://www.newscientistjobs.com/

Sage Bionetworks (Synapse, a computational research environment developed by Sage Bionetworks)
http://www.nature.com/news/open-data-project-aims-to-ease-the-way-for-genomic-research-1.10507?WT.ec_id=NEWS-20120501
http://www.sagebase.org/info/careers.php

http://www.lifetechnologies.com/careers.html
http://www.newscientistjobs.com/jobs/job/staff-scientist-bioinformatics-united-states-1401205026.htm

University coop advisors

http://www.phosphonet.ca/  http://www.ubcneurology.com/Staff%20Web%20Pages/Staff_Web_Pages_SPelech.html

http://gladstone.interviewexchange.com/jobofferdetails.jsp;jsessionid=A7DC955143026E85E12A32908502B0FB?JOBID=25999

http://www.can.ubc.ca/get-involved/career-opportunities/

http://www.bioplanet.com/

http://bioinformatics.ramapo.edu/employment/index.html

SGS Canada Inc
http://www.ca.sgs.com/

Response Biomedical Corporation
http://www.responsebio.com/contact.asp

Centre for Addiction and Mental Health
http://www.ctv.ca/CTVNews/Health/20111128/campbell-donation-CAMH-111128/

University of Manitoba
http://home.cc.umanitoba.ca/~frist/PDFJobDescription.html

DNA Nexus
https://dnanexus.com/careers/puzzles

Microsoft research
http://research.microsoft.com/en-us/

Butte Lab
http://buttelab.stanford.edu/people:abutte

Su Lab
http://sulab.org/

Optra systems
http://www.optrainc.com/

GenoLogics Life Sciences Software
GenoLogics

Gene Security Network
http://www.blogger.com/www.linkedin.com/company/gene-security-network

Miragen
MicroRNA (miRNA) company Miragen Therapeutics of Boulder, Colorado

http://www.employment.gov.bc.ca/

Li Ka Shing Knowledge Institute
St. Michael’s Hospital, Toronto, Ontario
http://www.blogger.com/www.stmichaelshospital.com/knowledgeinstitute/

GlaxoSmithKline Inc.
http://www.gsk.ca/english/html/careers/index.html

CLC bio, Toronto Ontario
http://www.clcbio.com/index.php?id=11

Jackson labs
https://jax.silkroad.com/epostings/index.cfm?fuseaction=app.welcome&category_id=49415&company_id=15987&version=1&startflag=2&parent=Research%2FResearch%20Support%3B%3B%3BBioinformatics%20Core&levelid2=49415

Lignol biorefineries
http://www.lignol.ca/

Aquinox Pharmaceuticals
http://www.aqxpharma.com/

Vancouver Island Technology Park
http://vitp.ca/current-companies/


University of Manitoba
Manitoba Institute of Child Health

http://ca.indeed.com/

http://www.bioinformatics.ubc.ca/category/opportunities/jobs

University of Victoria

10th Annual BioPartnering North America
http://www.techvision.com/bpn/participants/index.php?pageid=34

AstraZeneca
http://www.astrazeneca.ca/en/joinus/jobs.asp

Applied Biological Materials
Applied Biological Materials Inc.

BC BioEnergy
http://www.bcbioenergy.com/newsevents/news-releases/

Cardiome
http://www.cardiome.com/about-us

iData Research
http://www.idataresearch.net/idata/Aboutus.php

ZEMA ZEPowerGroup
http://www.ze.com/

Accelrys -  leading scientific enterprise R&D software and services company, supports industries and organizations that rely on scientific innovation to differentiate themselves
http://accelrys.com/

Quintiles
http://www.quintiles.com/about-us/

UBC symplicity
https://ubc-csm.symplicity.com/students/index.php

Genetrack Biolabs (Largest DNA testing service)
http://www.genetrackcanada.com/contact.php

Eli Lilly Pharmaceuticals
https://www.lilly.co.uk/about-us

indeed
http://ca.indeed.com/Bioinformatics-jobs

PerkinElmer
http://www.geospiza.com/Company/careers.shtml

Henry M. Jackson Foundation (Biotechnology High Performance Computing Software Applications Institute (BHSAI))
www.bhsai.org

Ingenuity Systems
www.ingenuity.com/company/careers.html

the Systems Biology Institute
http://sbi.jp

SRA
http://www.sra.com/

Glassdoor
http://www.glassdoor.com

Novadaq Technologies Inc
www.novadaq.com/  

T-Net
http://www.bctechnology.com/scripts/search_form.cfm

CareerJet
http://www.careerjet.ca/health-informatics-jobs/british-columbia-3086.html

Syreon
http://ch.tbe.taleo.net/CH01/ats/careers/requisition.jsp?org=SYREON&cws=1&rid=64

SBN
http://thesbn.ca/Sponsors/index.htm
http://thesbn.ca/Members/employers

BC Public Service
Ministry of Health
https://search.employment.gov.bc.ca/cgi-bin/a/searchjobs_quick.cgi

Broad institute of MIT and Harvard
http://www.broadinstitute.org/careers/career-center

http://bioinformatics.utoronto.ca/jobs

2012 Bioinformatics and Computational Biology Competition
http://www.genomecanada.ca/en/portfolio/research/2012-bcb-competition.aspx
http://www.genomecanada.ca/medias/PDF/en/2012-bcb-competition-list-registrants.pdf

1.            $335 M – Xenon Pharmaceuticals Inc.
2.            $140 M – Tekmira Pharmaceuticals Corporation
3.            $35 M – Welichem Biotech Inc.
4.            $11 M – Zymeworks Inc.
5.            $10 M – Allon Therapeutics Inc.
6.            $8.3 M – Protox Therapeutics Inc.
7.            $5.5 M – EnWave Corporation
8.            $4.6 M – Neovasc Inc.
9.            $2.6 M – iCo Therapeutics Inc.
10.          $2.5 M – biOasis Technologies Inc.

CHARLES PERKINS CENTRE SYSTEMS BIOLOGY LAB

RIM

Working at RIM: A Student's Perspective
http://coopcommunity.sfu.ca/modules.php?op=modload&name=News&file=article&sid=524&mode=thread&order=0&thold=0

Mozilla Plugins

http://blogs.techrepublic.com.com/howdoi/?p=199

~/.mozilla/plugins/libflashplayer.so

free online mindmap
http://bubbl.us/edit.php

Tuesday, February 2, 2010

Number properties - Commutative, associative

Commutative - order - 4+5 = 5+4
Associative - grouping - (4 + 5) + 6 = 5 + (4 + 6)
http://www.onlinemathlearning.com/number-properties.html

http://en.wikipedia.org/wiki/Idempotence
In computer science, the term idempotent is used to describe methods or subroutine calls that can safely be called multiple times, as invoking the procedure a single time or multiple times has the same result; i.e., after any number of method calls all variables have the same value as they did after the first call.
eg. table lookups

http://en.wikipedia.org/wiki/Atomicity_(database_systems)
atomic transaction, a series of database operations either all occur, or nothing occurs.

http://en.wikipedia.org/wiki/Deterministic_system_(mathematics)
In mathematics, a deterministic system is a system in which no randomness is involved in the development of future states of the system

OS / Architecture conferences

OSDI - Operating Systems Design and Implementation
http://www.usenix.org/events/osdi08/tech/

WIOSCA - Workshop on the Interaction between Operating Systems and Computer Architecture
http://www.ideal.ece.ufl.edu/workshops/wiosca09/

PESPMA Workshop on Parallel Execution of Sequential Programs on Multi-core Architectures (Beijing, China)
http://cccp.eecs.umich.edu/pespma

Monday, February 1, 2010

http://www.doodle.com/ for scheduling planning signup events

http://www.doodle.com/
-- for scheduling events.

Counting Permutations and Combinations

http://www.andrews.edu/~calkins/math/webtexts/prod02.htm

Permutations

Permutation is another name for possible arrangements with SOME items from a given set. It is important to remember that order chosen or position arranged is taken into account. Hence permutations are similar to anagrams. Given below is the necessary equation.
nPr = n! / (n - r)!
where r is the number of items arranged from n elements.

Example: How many ways can you arrange four figurines from a set of seven?
Answer: 7P4=7!/3!=7•6•5•4=840.
Alternate solution: The figurines can be placed as follows: 7 6 5 4 , which is the same as the factorial notation 7!/3!.

http://freeonlinecalculator.net/calculators/discretemathematics/permutations.php

P(8,5) = 8! / (8 - 5)! =
6,720

Combinations

Combinations are arrangements of elements without regard to their order or position.
nCr = n! / (r!(n - r)!)
where r is the number of items taken from n elements.
Note that these numbers are the same as those in Pascal's Triangle, the binomial formula, and the binomial distribution. Those less than about four digits should become very familiar.

Example: You have five places left for stamps in your stamp book and you have eight stamps. How many different ways can you select five?
Answer: 8!/(5!3!) = 8•7•6/(3•2)=56.
Think of putting them in slots, the first has eight choices, the next slot has seven choices and so forth as demonstrated.
8 7 6 5 4

Each combination of choosing 5 out of the 8 has permutations of its own. The five can be arranged in the following ways:
5 4 3 2 1

Thus there are (8!÷3!)÷5! = 8!÷(5!3!)=56 ways to select five of eight, but 6720 ways to arrange five of eight.

C(8,5) = 8! / 5! (8 - 5)! =
56

Unique dice combinations, 6+5+4+3+2+1 = 21, it's like a triangle
for dice with only 4 dots ...
(1,1) (1,2) (1,3) (1,4)
(2,1) (2,2) (2,3) (2,4)
(3,1) (3,2) (3,3) (3,4)
(4,1) (4,2) (4,3) (4,4)

so you can draw a diagonal and you don't count one side of the triangle, so first row has 1, second row has 2, third row has 3, fourth row has 4 so 1+2+3+4 = 10